Fioricet is a combination medication that contains acetaminophen, butalbital, and caffeine, primarily used to treat tension headaches and migraines. The acetaminophen component provides pain relief, while butalbital, a barbiturate, helps to relax muscle contractions that can contribute to headache pain. Caffeine enhances the effectiveness of acetaminophen and butalbital by constricting blood vessels and improving their absorption.

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